tacero case study zs

Don't worry! Tips: Practice case studies from Case In Point,Vault's Guide,Online Resources etc. Jain N, Kotla S, Little BB, et al. Harel Z, Harel S, Shah PS, Wald R, Perl J, Bell CM. Rev Esp Enferm Dig 2013;105:232-234. Am J Med 2013;126(3):264.e9–264.e24. Adverse Events during Initial Phase and Maintenance Phase. J Card Fail 2004;10:297-303, 6. Adv Chronic Kidney Dis 2014;21:247-247. — both in Australia; ZS Pharma, Coppell (H.S.R., B.S. Patients in the ZS-9 group in whom a serum potassium level of 3.5 to 4.9 mmol per liter was reached at 48 hours were randomly assigned in a 1:1 ratio, with blinding preserved, to receive either their original ZS-9 dose or placebo once daily before breakfast on days 3 to 14 (maintenance phase). However, the QTc interval in this patient returned to the baseline level during the maintenance phase after ciprofloxacin was discontinued. The ZS Associates Interview Case Study is the third round of ZS Recruitment Process. Goraya N, Simoni J, Jo CH, Wesson DE. Competition – The client has a 10% market share and a relative market share of about 1 (if asked, you may explain that relative market share is the ratio of the company’s market share to that of its nearest competitor.). The company runs as a service (SaaS) or cloud business in computing. Consulting Firm: ZS Associates final round full time job interview. Aldosterone antagonists for preventing the progression of chronic kidney disease. Industry Coverage: e-commerce, online business; retail. Assets – Since the firm has been building toys by hand, the fixed assets are essentially only the land and improvements. Castillo-Cejas MD, De-Torres-Ramirez I, Alonso-Cotoner C. Colonic necrosis due to calcium polystyrene sulfonate (Kalimate) not suspended in sorbitol. Business Case studies are usually real-life business situations. The total visits = 200+300+300+400 = 1200 (Excluding the Easies one). What would the value of the company be if the owner invests in the new technology. that ZS was looking for from a collaboration platform, with mobility functionality and video conferencing. S3A in the Supplementary Appendix). Thus the number of sales people to be allotted to this task is 1500/12=125. Costs – Material accounts for 10% of the direct cost, while labor accounts for the other 90%. 22. Ahn SY, Ryu J, Baek SH, et al. In this round, the interviewer aims to judge the following characteristics of a candidate as mentioned in the ZS Business Consulting Website:-, Orientation to quality and creating positive impact. Improve the quality of employee data in SuccessFactors Employee Central . So you must assimilate all the customer segmentation, product and pricing data into the total market size. Up until now, he has been in the business of building high-quality, handcrafted toys largely by hand with a skilled labor force. ZS Associates, founded by Andris Zoltners and Prabhakant Sinha in 1983, is a sales and marketing consulting and outsourcing firm headquartered in Evanston, Illinois, US.The firm also provides staff augmentation & technology services for clients primarily in the Pharmaceutical Industry. These questions are mainly guesstimates, brain teasers, and behavioral questions. During the maintenance phase, adverse events were reported in 25.1% of patients receiving ZS-9 and in 24.5% of those receiving placebo. No other clinically significant changes in vital signs or in levels of blood glucose or electrolytes other than potassium were observed throughout the study, nor was there evidence of increased blood pressure, body weight, or edema (Table S5 in the Supplementary Appendix). Since the property was held for 48 years, the current value will be $100K * (2 x 2 x 2 x 2) = $1.6M. Mean increases in the QTc interval ranged from 0.03 msec at the lowest ZS-9 dose (1.25 g) to 7.61 msec at the highest ZS-9 dose (10 g) on study day 2, and from 0.38 msec at the lowest ZS-9 dose to 10.3 msec at the highest ZS-9 dose on study day 3. ), San Antonio — all in Texas; Boston Biostatistics Research Foundation, Framingham, MA (P.T.L. ZS decided to develop its REVO integrated analytics platform on the AWS Cloud. Firstly, calculate the number of visits for each type of warehouse. Fixed costs for the business are $700,000 per year. Harvard Business Case Studies Solutions - Assignment Help. We used a predefined closed testing procedure, in which we first tested the highest dose in the initial phase, then the corresponding highest dose in the maintenance phase, then the next highest dose in the initial phase and then in the maintenance phase, until the lowest dose was reached. Vardeny O, Claggett B, Anand I, et al. The most trusted, influential source of new medical knowledge and clinical best practices in the world. Can a mechanical device at a time t. S and of. Proprietary Nature of Technology – The new toy-making technology is being offered for sale by a machine tool company, who holds the patent. Chapters (II) and (III) summarizes all the case studies into nine aspects, each aiming to represent different aspects of the blue economy. “The Extended L ive Case Appro ach To T eaching Mar keting Research,” Exploring disturbance hypothesis intermediate » thesis literature definition » pay to do dissertation » Zs associates case study. 18. In this multicenter, two-stage, double-blind, phase 3 trial, we randomly assigned 753 patients with hyperkalemia to receive either ZS-9 (at a dose of 1.25 g, 2.5 g, 5 g, or 10 g) or placebo three times daily for 48 hours. The software is used for tracking patient outcomes and utilizes an extensive database and proprietary analytics to recommend procedures based on patient comorbidities (In medicine, comorbidity is the presence of one or more additional diseases or disorders co-occurring with a primary disease or disorder). If this is the case, price will also fall as competition cuts price in an attempt to gain share. Top teams receive opportunities for pre-placement interviews, pre-placement offers, prizes and a chance to showcase their work to ZS leaders. Holy Mary Pray For Us: the Relationships Between the Neapolitan Church and the Camorra, and the ‘Devotion’ of Local Criminals Tamara Colacicco In my paper I focus on the case study of the Camorra and malavita from the 1950s until today. Yang A, Leon A, Nuttall M, Low J, Rasmussen H. In vitro ion exchange capacity and selectivity of ZS-9, a novel, selective cation trap for the treatment of hyperkalemia. Clin J Am Soc Nephrol 2013;8:371-381, 27. During the initial phase of the study (Panel A), mean potassium levels in patients who received either 5 g or 10 g of ZS-9 three times daily, as compared with placebo, were significantly reduced at most time points (as indicated by asterisks). The potassium-lowering action of ZS-9 is based on size-selective micropores in the zirconium silicate crystal structure, which traps potassium in the intestinal tract in exchange for protons and sodium. CrossRef Google Scholar G+Youtube InstagramLinkedinTelegram, [email protected]+91-8448440710Text Us on Facebook. Full inclusion and exclusion criteria are provided in the complete study protocol, available at NEJM.org. The authorized source of trusted medical research and education for the Chinese-language medical community. Queson what is the mass on the part of such figures, obtained by multiplying their magnitudes and angles. Practice 70 to 80 puzzles available in Geeks for Geeks. These are owned outright by the company. S1 in the Supplementary Appendix, available with the full text of this article at NEJM.org).16 In a phase 2 study, ZS-9, as compared with placebo, was associated with significant reductions in serum potassium levels within the first 48 hours of treatment in patients with stage 3 chronic kidney disease (estimated glomerular filtration rate [eGFR], 30 to 60 ml per minute per 1.73 m2 of body-surface area) and serum potassium levels of 5 to 6 mmol per liter.17 Here, we report the results of a phase 3, two-stage, double-blind, randomized, placebo-controlled, dose-ranging trial of ZS-9 for the treatment of hyperkalemia. Since the company has no proprietary control over the technology, it is likely that competitors will also acquire it, resulting in an overall lowering of the industry cost structure. Navaneethan SD, Nigwekar SU, Sehgal AR, Strippoli GF. All concomitant medications were kept constant throughout the study, including diuretic agents, RAAS inhibitors, and antidiabetic therapies. Round: Case Study Interview Round 3: (Case study round) It started around morning 7:30 am and since then we were ready with our resumes and folder including documents of results and certifications. Take the following steps to analyze this data: The following steps can help add more context to your analysis. Sufficient time provided Tips: Practice for aptitude from various sites or books if you are slow. Assume all assets are fully depreciated and ignore taxes. Then we must prioritize the warehouses which are providing more profits to the company. Thus the total visits = 200+300+300+400+300 = 1500, And the number of visits by a single person is 12 visits/week. It depends on your job profile. Dietary management of chronic kidney disease: protein restriction and beyond. The efficacy end point for the maintenance phase was the between-group difference in the mean serum potassium level during the 12-day treatment interval, which was analyzed separately for each of the four dose groups in the initial phase, as compared with the corresponding placebo group. The decline in the potassium level was rapid and dose-dependent, starting at a dose of 2.5 g three times daily. The total population of the country amounted to 4 million (2004 Moldovan census). Our results indicate that ZS-9 is a potent, selective potassium trap that corrects hyperkalemia within 48 hours. Mean increases in the QTc interval ranged from 0.03 msec at the lowest ZS-9 dose (1.25 g) to 7.61 msec at the highest ZS-9 dose (10 g) on study day 2, and from 0.38 msec at the lowest ZS … 3. During the maintenance phase, both the 5-g and 10-g daily doses of ZS-9 were significantly superior to placebo in maintaining normokalemia (P=0.008 and P<0.001, respectively), with hyperkalemia recurring in patients assigned to placebo who had received 5 g or 10 g of ZS-9 during the initial phase (Figure 3B and 3C). ZS Associates, founded by Andris Zoltners and Prabhakant Sinha in 1983, is a sales and marketing consulting and outsourcing firm headquartered in Evanston, Illinois, US.The firm also provides staff augmentation & technology services for clients primarily in the Pharmaceutical Industry. That’s thenext natural issue. What strategic alternatives should the owner of the toys business consider? Since the assets ($1.6M) are higher than the value of the discounted cash flows ($1M), then it would make more sense to liquidate the business and sell the assets. We recognise that, depending on the type of use, the boot industry is split into two divisions and the clients are segmented by occupation. Industry Coverage: e-commerce, online business; retail. Mayo Clin Proc 2013;88:987-995, 29. The primary efficacy end point for the initial phase was the between-group difference in the exponential rate of change in the mean serum potassium level during the first 48 hours of treatment. Dmitrienko A, Tamhane AC, Wang X, Chen X. Stepwise gatekeeping procedures in clinical trial applications. — both in California; and Denver Nephrologists, Denver, (G.B.). Hemanth asked on May 26, 2019 - 1 answer Write an answer. Other end points are described in the study protocol. Proc (Bayl Univ Med Cent) 2010;23:239-245, 9. There were no cases of a decrease in potassium levels of more than 3.0 mmol per liter. The Campus Beats Case Challenge tests students’ analytical and problem-solving skills. We also conducted subgroup analyses for patients with a combination of heart failure, diabetes mellitus, and reduced renal function (eGFR, <60 ml per minute per 1.73 m2) (Table S2 and Fig. Adverse events were reported in 12.9% of patients in the ZS-9 group and 10.8% of those in the placebo group during the initial phase (Table 2, and Table S3 in the Supplementary Appendix). 5. This online interview is almost 40-50 mins long and consists of 7-8 video questions and 3-4 written questions. In considering the problem of the development of the Renaissance outside Italy, some scholars have adapted concepts such as diffusion from the disciplines of geography and anthropology to the purposes of art-historical inquiry. Started in 1965, ChemCo is a leading manufacturer of car batteries in the U.K. market. Concise summaries and expert physician commentary that busy clinicians need to enhance patient care. Along with customized big data, analytics, AI and machine learning (ML), and orchestration tools, it adopted core AWS services such as Amazon Elastic Compute Cloud (Amazon EC2) for launching applications and Amazon Relational Database Service (Amazon RDS) for scaling its database. Study stopping rules are included in the protocol. All the authors vouch for the accuracy and completeness of the data and the analyses. The job profile you will select while filling the form the case study questions will be also asked related to this. Zs associates case study for essay my pet bird parrot. 292–313). We help students to prepare for placements with the best study material, online classes, Sectional Statistics for better focus and Success stories & tips by Toppers on PrepInsta. This round holds the highest importance in the entire ZS Associates Selection Process. Normokalemia was reached on average in all three dose groups within 48 hours (P<0.001 for all comparisons with placebo). same number of people at every age. The Evanston-based company began operations in 1983 and currently has over five thousand consultants in the Americas, Europe, and Asia. For numerous case studies, you wouldn’t have any right or wrong answer to judge. Round 3: (Case study round) It started around morning 7:30 am and since then we were ready with our resumes and folder including documents of results and certifications. Palmer BF, Fenves AZ. Similarly, after each dose of ZS-9 was discontinued at day 15, hyperkalemia redeveloped within 1 week after treatment discontinuation. Role of dietary salt and potassium intake in cardiovascular health and disease: a review of the evidence. Rate Us. Brand Impact – The candidate may argue that machine-made toys might negatively impact Digilant Toys’s brand. Started in 1965, ChemCo is a leading manufacturer of car batteries in the U.K. market. The most effective and engaging way for clinicians to learn, improve their practice, and prepare for board exams. Acute and chronic cardiovascular effects of hyperkalemia: new insights into prevention and clinical management. It is a premium quality soap popular among the Upper-Class population. A candidate needs to imagine, handle and summarize a complex business situation or dilemma. Rates of adverse events were similar in the ZS-9 group and the placebo group (12.9% and 10.8%, respectively, in the initial phase; 25.1% and 24.5%, respectively, in the maintenance phase). Ash SR, Singh B, Lavin PT, Stavros F, Rasmussen HS. A dose-dependent increase in serum bicarbonate was observed, which was consistent with the effect of a decrease in serum potassium. Diet and kidney disease in high-risk individuals with type 2 diabetes mellitus. Views:326005. NEW! Hence, WSA is committed to share its organisational profile, reports and project-specific information to target groups and stakeholders, as well as to the entire community residing in the intervention areas. Disclosure forms provided by the authors are available with the full text of this article at NEJM.org. Steps. Mean increases in the QTc interval ranged from 0.03 msec at the lowest ZS-9 dose (1.25 g) to 7.61 msec at the highest ZS-9 dose (10 g) on study day 2, and from 0.38 msec at the lowest ZS … In Market Sizing, there will be large amount of information provided to the candidates that would require a quick assessment and analysis. – If asked about any exogenous factors, simply tell the candidate to assume that the market is expected to continue as it currently is. Treatment of metabolic acidosis in patients with stage 3 chronic kidney disease with fruits and vegetables or oral bicarbonate reduces urine angiotensinogen and preserves glomerular filtration rate. Patients assigned to the placebo group in the initial phase were randomly assigned to receive either 1.25 g or 2.5 g of ZS-9 in the maintenance phase (Figure 1). 22 ZS Associates Decision Analyst Associate interview questions and 23 interview reviews. We had an hour to go through the case study … ZS Associates Case Study. The drug was equally effective across various subgroups, including patients with a combination of heart failure, chronic kidney disease, and diabetes. Impact of the global crisis on the internationalization of Estonian firms: A case study. Thus the preference order will be Big Money>Tough Ones>Smart Buys>Friendlies>Easies. Uribarri J, Oh MS. Case Type: marketing strategy. DOI: 10.1056/NEJMoa1411487, Tap into groundbreaking research and clinically relevant insights. Estacio RO. St Peter WL, Odum LE, Whaley-Connell AT. However, there remain several gaps in … Svensson M, Gustafsson F, Galatius S, Hildebrandt PR, Atar D. How prevalent is hyperkalemia and renal dysfunction during treatment with spironolactone in patients with congestive heart failure? When the 10-g dose was discontinued after day 15, hyperkalemia redeveloped in patients within 1 week. You can expect to hear some of the following questions: 1. It is said that case should be read two times. To understand the market, you ask the interviewer how big it is. Sort by. These agents have uncertain efficacy and generally poor side-effect profiles and have been associated with serious gastrointestinal adverse events,19,20 particularly when administered with sorbitol.21-24 In patients with less severe, chronic hyperkalemia, a common early intervention is to limit potassium intake. Read 50 case studies, success stories, & customer stories of individual ZS Associates customers - their use cases, successful stories, approaches, and end results software. All statistical analyses were performed on serum measurements from the central laboratory. Patients with hyperkalemia who received ZS-9, as compared with those who received placebo, had a significant reduction in potassium levels at 48 hours, with normokalemia maintained during 12 days of maintenance therapy. Address reprint requests to Dr. Packham at the Melbourne Renal Research Group, 73 Pine St., Reservoir, VIC 3073, Australia, or at [email protected]. However, a low-potassium diet is restrictive and deprives patients of many food choices that are otherwise associated with improved renal outcomes.25-30 Among patients who are receiving RAAS inhibitors or who would benefit from the protective effects of these drugs, hyperkalemia prevents the most effective therapy at the full target dose. Some situation based and some guess estimates were also asked. Kidney Int 2012;81:7-9, January 15, 2015N Engl J Med 2015; 372:222-231 Finally, since the study was conducted among ambulatory outpatients, it excluded hospitalized patients and those receiving dialysis. Sodium Zirconium Cyclosilicate in Hyperkalemia. Age Distribution: assume a flat age distribution, i.e. Get a clearer perspective on solving Case Studies with these solved examples. JAMA Intern Med 2013;173:1682-1692, 28. Youth — An Emerging Public Health Challenge, Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant, Spread of a Variant SARS-CoV-2 in Long-Term Care Facilities in England, Once-Weekly Semaglutide in Adults with Overweight or Obesity, Case 8-2021: A 34-Year-Old Woman with Cholangiocarcinoma, Extrahepatic Manifestations of Chronic HCV Infection. Sales & Marketing Case Study | Authors :: Robert E. Spekman, Sameer Kumar, Arya … Accenture HR Audit and Compliance as-a-service (AHRACaas) powered by SAP HANA Cloud Platform (HCP) ZS Associates, headquartered in Evanston, Illinois, is a sales and marketing consulting firm with over 5,000 employees in 13 countries. Khanagavi J, Gupta T, Aronow WS, et al. The reduction in serum potassium levels with ZS-9 was most pronounced in patients with the highest potassium levels at baseline. Aaron KJ, Sanders PW. All patients provided written informed consent. Sort by. You received the following information and are expected to solve your clients questions: Digilant Toys is a high-end toys maker in the country of Moldova. Participants enter as a team and refine their business acumen by thinking through real-world scenarios. About ZS Associates. First step is to understand what consulting is. Stojiljkovic L, Behnia R. Role of renin angiotensin system inhibitors in cardiovascular and renal protection: a lesson from clinical trials. Study drug dose adjustment during the study was not allowed. Patients were excluded if they were receiving dialysis, had diabetic ketoacidosis, had a potassium level of more than 6.5 mmol per liter, had cardiac arrhythmia that required immediate treatment, or had received organic polymer resins or phosphate binders within 1 week before enrollment. Am J Cardiol 2012;109:1510-1513, 4. A salesperson visiting warehouses can make 12 visits/week. ’m worried about what this means for my business, and want your advice. Peer-reviewed journal featuring in-depth articles to accelerate the transformation of health care delivery. Design/methodology/approach – The paper takes a case study approach, following the development of the training program and changes implemented throughout the first two years of operation. They are not offering exclusivity to any customers (i.e. Sodium zirconium cyclosilicate (ZS-9) is a highly selective cation exchanger that entraps potassium in the intestinal tract in exchange for sodium and hydrogen (Fig. The type I error for multiple testing of doses and end points was prospectively defined.18 We compared the between-group difference in efficacy using a generalized estimating equation model for continuous end points and a two-sided Fisher's exact test for binary outcomes. All the authors had access to the complete study data, which were held by the sponsor, ZS Pharma. Information, resources, and support needed to approach rotations - and life as a resident. According to ZS’ business consulting career website, they look for the following six core skills: Excellent critical thinking and problem-solving Desire to innovate and … The client is preparing to launch their revolutionary Healthcare Cloud software to market and is seeking our advice on how to maximize revenue. N Engl J Med 1999;341:709-717, 16. ZS-9 effectively normalized potassium levels in patients who were receiving RAAS inhibitors for the treatment of cardiovascular or renal disease, a group in which a dose reduction or discontinuation of these drugs is often needed. For tests of the primary efficacy end point during the two phases, the study had a power of 90% with a two-tailed type I error rate of 0.05. Market Trends, Regulation, etc. The following data is also provided to you: The following market details are also given: You as a manager of the consultancy firm are supposed to answer these questions: We need to decide firstly whether to stay in the toys business at all and if so, whether he uses the new technology: Option 1: Sell the business to a third party, Option 2: Sell the assets of the company and shut it down, Option 4: Keep operating and invest in the new technology. Investment – Investing in the new technology will cost the firm $1M. So the introduction of the new technology to the market might be expected to reduce industry profits, making this business completely unprofitable. Harvard Case Study Solutions. The case study round is the 3rd round in the recruitment process after the aptitude test and the video interview (It is the 2nd round in case of referrals/off campus). I run a small coffee shop that has been in my family for over 30 years.Recently, I learned that Starbucks has bought the lease on a unit just around the corner.Starbucks will be opening in 3 months’ time.
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